• Brain Synchrony: Mood and anger regulation
  • Temperature regulation: affects Thyroid and metabolism
  • Sleep regulation: converted to melatonin
  • Appetite: carbohydrate stimulates production, present in Gastro Intestinal (GI) tract and affects GI motility
  • Pain modulation
  • Vasoconstriction
Food habits and Weight Management
  • Controls rhythm and tiredness – via conversion to melatonin and leads to proper rest and recuperation
  • Controls hunger – low serotonin leads to increased Ghrelin which controls feelings of hunger
  • Low serotonin leads to carbohydrate and salty foods cravings
Hormonal interactions
  • Interacts with Progesterone, Growth Hormone, Pregnenolone, Leptin, Aldosterone
  • Serotonin controls T3 production and TSH release
  • Thyroid hormones determine serotonin levels (low TSH, T4 or T3 leads to low serotonin)
  • Serotonin primes estrogen receptors
  • Loss of coordinated development affects mind-body connection, causing headaches, backaches, insomnia and depression
  • Anger and aggression
  • Depression and guilt, OCD, Bipolar, Anxiety
  • Migraines, food issues and IBS
  • Tinnitus, Fibromyalgia
  • Intense religious experiences
  • Self-esteem: shyness, inferiority complex, nervousness, vulnerable to criticism and fear of being disliked, fear of social contact
  • Excess may be caused by estrogen dominance
Symptoms of deficiency
  • Loss of pleasure in hobbies, interests and favourite activities and loss of enjoyment of life, friendships and relationships
  • Overwhelm and feelings of too many ideas to manage
  • Inner rage, inner paranoia, depression
  • Unable to fall into deep sleep (due to melatonin deficiency); SAD
Causes of deficiency
  • Inflammation and chronic health issues
  • Gluten sensitivity affects serotonin receptors
  • Insulin surges
  • Low nutrients: Vitamins B6 & B12, Zinc, Magnesium
  • Low protein and sources of tryptophan in diet
  • Excess caffeine and stress
Food modulators
Herb and supplement modulators 5HTP, St John’s, Wort, SAMe, Inositol

Adapted from:

Braverman, E. (2009). Younger (Thinner) You Diet. New York, N.Y.:Rodale.

Kharrazian, D. (2013). Why Isn’t My Brain Working? Carlsbad, C.A.: Elephant Press

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